Stem cell therapy
Mesenchymal stem cells derived from Wharton’s Jelly.
Wharton’s Jelly is the connective tissue of the umbilical cord. Mesenchymal stem cells derived from it will sit at the centre of the programme.

The flagship programme
Therapies planned around one idea: the body already knows how to renew itself.
Artist’s rendering
The approach
Regenerative medicine works with material the body already uses to repair itself: cells, plasma, and the signals that pass between them.
At Ponce de León, these therapies will be prepared and given by physicians, in a clinical setting, as part of a stay designed for rest.
Each plan will begin with a remote consultation before travel. A physician will decide with each guest whether a therapy is suitable.
Planned therapies
Guests will typically follow one therapy, or a small combination, chosen with their physician.
Mesenchymal stem cells derived from Wharton’s Jelly.
Wharton’s Jelly is the connective tissue of the umbilical cord. Mesenchymal stem cells derived from it will sit at the centre of the programme.
PRP, delivered with image guidance.
Platelet-rich plasma is prepared from a small sample of a guest’s own blood. It will be delivered by a physician using image guidance.
Therapies based on the signals cells send one another.
Exosomes are small vesicles that cells release to communicate. Exosome-based therapies will be offered alongside the cell and plasma treatments.
Shoulder and other joints.
Shoulder treatments will be planned in two forms, within the joint and within the tendon. Other joints will be assessed individually.
Facet and epidural injections.
Facet and epidural injections will be planned segment by segment, with each plan set by the treating physician.
Hyperbaric oxygen and cryotherapy.
Hyperbaric oxygen sessions and cryotherapy will be available as part of a stay, in support of the main therapies.
For guests of the aesthetic programme.
Guests of the aesthetic surgery programme will be able to include regenerative therapies in their recovery plan, on their physician’s recommendation.

The stay
Time for consultation, treatment, and rest, without hurry.
Treatments will be given by Dominican physicians and anesthesiologists who work in English and Spanish.
Every guest will stay on the estate, with nursing and concierge close at hand.
Spa, pools, and a kitchen led by functional nutrition will be part of each day.
Opening Spring 2028
The estate will receive no more than ten guests at a time. Priority list members will hear first when consultations and reservations open.
Join the priority list